The new intraosseous device is here

Introducing the NIO™

The New Intraosseous device from the makers of The Emergency Bandage®

The NIO is an automatic intraosseous device packaged for safe, quick, and easy vascular access. No drills, no batteries, no extra parts.

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How does the NIO work?

Clinically Proven Success

Read some of the clinical research that has proven the NIO to be safe, easy-to-use, and the most reliable automatic IO system on the market. The NIO is scheduled to be evaluated within EMS services, major trauma hospital Emergency Departments, and several military organizations.

In a recent study, The New York Institute of Technology College of Osteopathic Medicine tested the NIO for efficacy rates, with regards to its ease of use and speed, and evaluated the overall effect on the insertion site. They found a 98% overall success rate in the Proximal Tibia, and 91% in the Humeral Head. Additional studies performed found zero occurrences of micro-fractures to the bone and an average procedure time of 18.3 seconds.

To read more clinical studies, please see our Case Studies page.

…the first attempt success rate for inserting an NIO in the tibia was 98%, Humerus 91%…

New York Institute of Technology College of Osteopathic Medicine

No statistically significant differences were observed between intraosseous and intravenous administration of morphine sulfate for nearly all of the pharmacokinetic parameters…

The American Journal of Emergency Medicine

The NIO is FDA approved, Health Canada certified, and has received a CE Mark.

How the NIO Works

The NIO is a simple, automatic intraosseous device ready to use for safe, quick, and easy vascular access.

  • 1

    Open the pack and remove the NIO.

  • 2

    Locate and disinfect injection site.

  • 3

    Place device approx. 2cm medially and 1cm proximally from tibial tuberosity

    Alternate site: humeral head. See videos for detail.

  • 4

    Unlock the NIO by rotating the cap 90 degrees in either direction.

  • 5

    Place dominant hand over cap, and press device against patient. While pressing down on the device with palm, pull trigger wings upwards with fingers.

  • 6

    Gently pull the NIO up in a rotating motion while holding the needle stabilizer against the insertion site.

  • 7

    Continue holding the needle stabilizer in place and pull up the stylet to remove.

Complete Instructions for Use

  1. Open the pack and take out the NIO. Make sure that the NIO is free of all packaging parts.
  2. Select one of the following injection sites:
    • Primary site for Intraosseous injection: Proximal tibia
      Approximately 1 inch or 2 cm medially and 1/2 inch or 1 cm proximally to the tibial tuberosity.
    • Secondary site for Intraosseous injection: Humeral Head
      Adduct the patient’s hand and locate the greater tubercle next to the head of the humerus.
      NOTE: To prevent accidental removal of the device, following the procedure immobilize the patient arm.
  3. Disinfect the skin on the injection site by following institutional protocols. Note that this is a two-handed procedure. Place your non-dominant hand on the textured dots located on the lower part of the NIO and position the NIO at a 90 degrees angle to the skin at the injection site. The non-dominant hand should maintain this position throughout this procedure.
  4. Unlock the NIO by rotating the cap 90 degrees in either direction.
  5. Place the palm of your dominant hand over the cap. Press the device against the patient’s skin and maintain downward pressure. While pressing down on the device, pull the trigger wings upwards. This action will activate the device.
  6. Gently pull the NIO up in a rotary motion while holding the base of the needle stabilizer against the insertion site.
  7. While holding the needle stabilizer and cannula in place, remove the stylet by pulling it up (use a twisting motion of the stylet if necessary). The keyhole notch on the distal end of the NIO can be used to assist in removing the stylet from the cannula. Place stylet into an appropriate biohazard container.
  8. Connect a syringe and confirm secure fitting. If desired, aspirate bone marrow. Always confirm successful needle placement by flushing with up to 20 cc of fluid or per your protocol. It is recommended to use the NIO Fixation sticker to affix the NIO stabilizer. (A). Connect any standard system for infusion (B). Cover the insertion site with a sterile, occlusive dressing.
  9. Removal instruction: Remove the cannula and needle stabilizer by twisting and pulling vertically. Dispose of the removed components in the appropriate biohazard container. Cover the insertion site with a sterile, occlusive, wound dressing.

Download foldable IFU printout sheet

Watch the NIO in Action

Case Studies

Read some of the clinical research that has proven the NIO to be safe, easy-to-use, and the most reliable automatic IO system on the market. The NIO is scheduled to be evaluated within EMS services, major trauma hospital Emergency Departments, and several military organizations.

… the first attempt success rate for inserting an NIO in the tibia was 98%, Humerus 91%…

New York Institute of Technology College of Osteopathic Medicine

In a recent study, The New York Institute of Technology College of Osteopathic Medicine tested the NIO and found a 98% overall success rate in the Proximal Tibia, and 91% in the Humeral Head. Additional studies performed found zero occurrences of micro-fractures to the bone and an average procedure time of 18.3 seconds.

The NIO is easy to learn, easy to teach, and one of the fastest methods of vascular access. We’ve developed the NIO alongside EMT personnel, military medics, first aid responders, and Emergency Departments worldwide. Case studies continue to show the benefits of intraosseous infusion and the NIO continues to excel in each study made.

Currently Available Studies

Browse through our list of currently available studies. Additional studies will be posted as made available and published. In some cases, a PerSys Medical generated summary is provided for unpublished or confidential studies.

  • Armée de Terre (French Army)

    Lyon, France

    The French Army conducted an evaluation of the NIO device and found 100% of the participants were satisfied by the NIO Adult’s implementation (being intuitive, fast, safe and ergonomic).

    Download Study Summary
  • New York Institute of Technology College of Osteopathic Medicine

    Old Westbury, New York, USA

    In a study hosted by the New York Institute of Technology College of Osteopathic Medicine, the NIO saw 98% success rate in the proximal tibia, and a 91% success rate in the humeral head.

    Download Study Summary
  • Georgia Regents University

    Augusta, GA, USA

    With a focus on usability, Georgia Regents Univeristy (then known as Georgia Health Sciences University) found users averaged a grade of 8.5 out of 10 on an ease of use of scale. The average time of procedure was 18.3 seconds.

    Download Study Summary
  • Morgue Central de Lima

    Lima, Peru

    The study in Lima, Peru included x-ray examination before and after each insertion; the study concluded that no bone fractures were found at any insertion site, even when a limb was used up to 5 times.

    Download Study Summary

Contact Us

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